Ran protein: A GTP-binding protein that works in conjunction with importins
RAN/GTP complexes bind to importins which causes disruption in the cargo/importin complex.
Karyopherin: A family of nuclear transport receptors that include importins and exportins
Examples of Karyopherin importins include Snurportin, Transportin, and Importin7.
Nuclear Localization Signals: a small stretch of amino acids that allow a protein to target the nucleus.
The first NLS mapped was by Alan Smith in 1984.
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